Researchers analysed 25,419 anonymised calls to a psychedelic support hotline from 2021 to 2026 and found cannabis users reported distress at the highest rate, 47.2%, above psilocybin and LSD.
A nonprofit runs a hotline for people who are mid-trip or coming down and feel things going wrong. Researchers turned six years of calls into a dataset of 25,419 interactions, larger than all published psychedelic clinical trials combined.
The most counterintuitive finding is cannabis: often treated as low-stakes, it had the highest rate of reported bad experiences, 47.2%.
One detail made me pause: whether a caller felt the volunteer was genuine was the strongest predictor of whether the call helped.
Curated from high-quality sources, with concise summaries and key takeaways.
